hepatitis c virus — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T39503	Hepatitis Virus C NS3 Protease Inhibitor 2
	Hepatitis Virus C NS3 Protease Inhibitor 2 is a peptide inhibitor derived from a product that targets the NS3 protease of the hepatitis C virus (HCV). Its inhibitory activity against the NS3 protease is characterized by ...
T25268	Coblopasvir		Others
	Coblopasvir is a pan-genotypic non-structural protein 5A (NS5A) inhibitor. It can be used to study chronic hepatitis C virus infection.		Others
T17190	U18666A		Others , HCV Protease
	U18666A is a cell-permeable drug and is a cholesterol synthesis and transport inhibitor. It inhibits replication of Ebola virus, dengue virus, and human hepatitis C virus.		Others , HCV Protease
T5S1598	Mulberroside C		Antioxidant , HCV Protease
	1. Mulberroside C has antioxidant activity.		Antioxidant , HCV Protease
T5938	4-Phenoxybenzylamine		HCV Protease
	4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against HCV NS3/4a .		HCV Protease
T3273	Bifendate	Bifendatatum	HBV , Reverse Transcriptase
	Bifendate (Bifendatatum) is commonly used to treat the transaminase elevation that caused by viral hepatitis and drug-induced liver injury.		HBV , Reverse Transcriptase
T9577	HCV-IN-31		HCV Protease
	HCV-IN-31 is a HCV inhibitor with an EC50/EC95 of 15.7 μM.		HCV Protease
T16088	MK-0608		HCV Protease
	MK-0608 is an orally bioavailable HCV replication inhibitor in vitro(EC50 = 0.3 μM and EC90=1.3 μM in the subgenomic-replicon assay).		HCV Protease
T6846	Vesatolimod	GS-9620	Apoptosis , HCV Protease , HBV , TLR , HIV Protease
	Vesatolimod (GS-9620) is an effective and specific orally active agonist of Toll-like receptor 7.		Apoptosis , HCV Protease , HBV , TLR , HIV Protease
T25268L	Coblopasvir dihydrochloride	Coblopasvir dihydrochloride(1312608-46-0 Free base)	HCV Protease
	Coblopasvir dihydrochloride can be used to study chronic HCV infection and is a pan-genotypic nonstructural protein 5A (NS5A) inhibitor.		HCV Protease
T11539	HCV-IN-29		HCV Protease
	HCV-IN-29 is a hepatitis C virus (HCV) inhibitor.		HCV Protease
T38237	2′-O-Methylcytidine		Nucleoside Antimetabolite/Analog , HCV Protease
	2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50= 3.8 μM).1It inhibits HCV replication in a replicon assay (IC50= 21.2 μM). 1.Migliaccio, G....		Nucleoside Antimetabolite/Analog , HCV Protease
T11541	HCV-IN-30		Others , HCV Protease
	HCV-IN-30 is an HCV NS5A replication complex inhibitor (IC50s: 901 and 102 nM for genotypes 1a and 1b replicons).		Others , HCV Protease
T15573	Inarigivir soproxil	SB9200	HCV Protease
	Inarigivir soproxil (SB9200) is an agonist of innate immunity. It also displays effective antiviral activity against resistant hepatitis C virus (HCV) variants (EC50s of 2.2 and 1.0 μM for HCV 1a/1b in cells of genotype ...		HCV Protease
T4544	Elbasvir	MK-8742	HCV Protease
	Elbasvir (MK-8742) is an inhibitor of nonstructural protein 5A (NS5A) of hepatitis C virus (HCV) being developed as a component of treatment regimens for chronic HCV infection.		HCV Protease
T7215	NM107	NM-107,2'-C-Methylcytidine	HCV Protease
	NM107 (2'-C-Methylcytidine) is a ribonucleoside with broad-spectrum antiviral activity, is an nucleoside inhibitor of the hepatitis C virus (HCV) NS5B polymerase, NM 107 in the wild-type replicon cells with the EC50 of 1...		HCV Protease
T3444	Merimepodib	VX-497,VI-21497	Dehydrogenase , Antiviral , HCV Protease , HBV
	Merimepodib (VX-497) is a novel noncompetitive inhibitor of Inosine monophosphate dehydrogenase(IMPDH).		Dehydrogenase , Antiviral , HCV Protease , HBV
T0013	Mecarbinate	Dimecarbine,Dimecarbin	HCV Protease
	Mecarbinate (Dimecarbin) is arbidol hydrochloride's chemical intermediate.		HCV Protease
T2770	Gentiopicroside	Gentiopicrin	P450 , HCV Protease
	Gentiopicroside (Gentiopicrin), a naturally occurring iridoid glycoside, extracted from Gentiana manshurica Kitag, inhibits P450 activity, with an IC50 and a Ki of 61 μM and 22.8 μM for CYP2A6; has antianti-inflammatorya...		P450 , HCV Protease
T1565	Deferiprone	Deferidone,CP20	Others , HCV Protease , Ferroptosis , UGT
	Deferiprone (Deferidone) is an Iron Chelator. The mechanism of action of deferiprone is as an Iron Chelating Activity.		Others , HCV Protease , Ferroptosis , UGT